Rat Model of Photochemically-Induced Posterior Ischemic Optic Neuropathy
نویسندگان
چکیده
منابع مشابه
posterior ischemic optic neuropathy following percutaneous nephrolithotomy
purpose: to report a case of posterior ischemic optic neuropathy (pion) following percutaneous nephrolithotomy (pcnl). patient and findings: a 57-year-old male who underwent pcnl because of renal stone was referred due to painless bilateral visual loss to the level of light perception immediately after the operation. the patient had history of diabetes mellitus, hyperlipidemia, and mild anemia....
متن کاملA novel rodent model of posterior ischemic optic neuropathy.
OBJECTIVES To develop a reliable, reproducible rat model of posterior ischemic optic neuropathy (PION) and study the cellular responses in the optic nerve and retina. METHODS Posterior ischemic optic neuropathy was induced in adult rats by photochemically induced ischemia. Retinal and optic nerve vasculature was examined by fluorescein isothiocyanate–dextran extravasation. Tissue sectioning a...
متن کاملPosterior ischemic optic neuropathy. II. Histopathology of the idiopathic form.
The optic nerve and chiasm, obtained at autopsy, from 53 cases with clinical histories of cerebrovascular disturbances were histopathologically investigated, and ischemic changes in the posterior portion of the optic nerve were revealed in 12 cases. The progress of posterior ischemic optic neuropathy might be divided into necrotic, liquefactive and scar stages. The lesions were located in the t...
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A 62-year-old female complained of vision loss following multiple abdominal surgeries for mesenteric ischemia. The patient’s visual acuity was no light perception (NLP) in the right eye and hand motion (HM) at 1’ in the left eye. Both pupils were unreactive and no relative afferent pupillary defect was noted. Anterior segment and fundus examination were unremarkable. T1 and T2 weighted MRI imag...
متن کاملDiffusion-weighted imaging in posterior ischemic optic neuropathy.
Optic Neuropathy We read with interest the case report by Mathur et al in which they have described an acute ischemic event in the posterior part of the intraorbital optic nerve consequent to rhinocerebral mucormycosis and its early detection by diffusion-weighted MR imaging (DW-MR imaging). In this regard, we would like to report another similar case that we came across in our tertiary care in...
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ژورنال
عنوان ژورنال: Journal of Visualized Experiments
سال: 2015
ISSN: 1940-087X
DOI: 10.3791/52402